The Mark III mixing desk used by the BBC in Chelmsford since 1986 is being replaced with new technology.
The desks, designed in the 1960s, were among the last to be designed and built by the BBC, and are still in operation at a handful of stations.
A Science Museum spokesman said the desk was an "exciting new acquisition".
John Liffen, of the museum, described the equipment as "a valuable device to explore how people's relationship with radio has changed over time".