The boat, docked in Little Venice, can sleep up to six people and comes with private use of a neighbouring garden.
It is just one of the quirky properties that visitors to the capital can enjoy after recent reforms to home sharing laws made it easier for Londoners to rent out their homes.
The reforms mean the city's residents can share their homes for up to 90 days a year without permission or registration.
modern design: house boat visitors can use the neighbouring garden
Other unusual properties in the capital include a four bedroom loft in a converted Victorian school, also priced at £500 per night.
The uniquely decorated home in Battersea boasts a huge open plan kitchen and dining room and two modern bathrooms.
For £150 per night, guests can enjoy an en suite bathroom and are given access to an extensive library. They will also have the use of a doorman.
The two bedroom apartment is a stone's throw from the West End's theatre quarter and the luxury shops of Regent Street.
Larger groups may choose to stay at a five bedroom town house in upmarketHampstead for £395 per night.
Smooth lines: the luxury penthouse in Soho
The Victorian property was recently refurbished and comes with a garden which has a stone seating area.
Those seeking more of the Made in Chelsea experience might opt for a two bedroom flat in west London.
For £229 per night, guests will have access to a hot tub and enjoy a chic interior.
Housing minister Brandon Lewis said previous legislation on short-term lets was "unworkable" and "outdated", adding; "I’m pleased we’ve been able to update the rules for the digital age of the 21st century".
He said: "This new law will unlock opportunities for this dynamic, growing sector and cements our commitment to be the world leader for the sharing economy."
All properties above are listed on AirBnB